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Choose the right organoid model and study system

Compare tumor PDOs, normal-tissue organoids and disease models by project goal, available assays and collaboration format. Browse options for supplied models, TRiCBIO-run studies and custom development.

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Matching models

PanCK, CD3 and DAPI profiling in renal tumor tissue and PDO 2.0 across culture time
Model & study servicesALI

Tumor PDO 2.0

An ALI-based tumor model for studying treatment response alongside source-tissue architecture and immune cells retained from the sample.

CD3CD4CD8
E-cadherin, LRP2 and Nephrin immunofluorescence for kidney organoid identity
Model & study services24-well

Human kidney organoids

Assess drug-related kidney injury using morphology, nephron markers and molecular readouts; the culture approach is selected by compound mechanism and priority endpoint.

E-cadherinLRP2Nephrin
SCGB1A1 (CC10), KRT5 and merged airway-cell marker readouts in normal lung organoids
Model & study services3D culture

Normal lung organoid

Human lung organoids for pulmonary-injury and candidate studies, combining airway and alveolar cell profiling with changes in tissue morphology.

SCGB1A1 (CC10)KRT5LysoTracker / ATII
Bright-field morphology of normal human gastric organoids
Model & study services3D culture

Normal gastric organoid

Study gastric epithelial biology and drug exposure in normal human organoids, with imaging of tissue structure, proliferation and mucin-related markers.

Ki67Mucin-associated IFEpithelial identity
Bright-field images of primary establishment and passage of human endometrial organoids
Tailored studies3D culture

Human endometrial organoid

Track morphology and marker expression from primary establishment and passaging through proliferative, secretory and receptive stages, with epithelial-identity profiling throughout.

E-cadherinKi67ER
Bright-field images of human fallopian tube organoids across time points and culture formats
Tailored studies3D culture

Human fallopian tube organoid

Human fallopian tube organoids with serial culture morphology and source-tissue/organoid H&E comparison, plus study-specific identity and functional assays.

H&EMorphologyStudy-specific markers
Budding morphology of mouse intestinal organoids across inflammatory cytokine conditions
Tailored studies3D intestinal organoid

IBD inflammation and barrier organoid model

For inflammatory bowel disease (IBD), established inflammation and barrier assays in mouse intestinal organoids support candidate comparison across morphology, permeability, viability and F-actin/ZO-1; we tailor a human study to the sample and program goal.

ZO-1F-actin
DAPI, ER and Ki67 staining in a breast cancer PDO
Model & study servicesPDO 1.0

Breast cancer PDO

Patient-derived breast tumor organoids for single-agent and combination studies, with PDO 2.0 / ALI considered when immune context is relevant.

ERPRKi67
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Organoid products & reagents

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