Core platform capability
Multimodal assays & QC
Combine morphology, histology, molecular and functional assays around the model and study objective so results can be interpreted together.
Assay capabilities
Combine morphology, function and molecular results around one study objective
Kidney-injury molecular assays, IBD barrier function, and renal-cancer PDO 2.0 histology and flow results span morphological, functional, molecular, and immune readouts. The final combination is defined by the model, mechanism, controls, and sample context.
View imageH9-derived | cisplatin molecular response: RT-qPCR profiles KIM-1, H2AFX and inflammation/stress-related genes across cisplatin conditions, helping prioritize kidney-injury biomarkers and define follow-on dose, timing and confirmatory assays.
TRiCBIO H9-derived kidney organoid cisplatin studyView the kidney organoid injury study
View imageBarrier permeability: FITC-Dextran imaging visualizes relative luminal fluorescence in mouse intestinal organoids across inflammatory conditions.
TRiCBIO mouse intestinal organoid studyView the IBD model and barrier study
View imageStudy readouts: source-tissue H&E, PDO 2.0 bright-field and H&E confirm morphology, while Annexin V/PI and CD3/CD8 flow cytometry compare conditions and define replication and mechanism follow-up.
TRiCBIO RCC PDO 2.0 study dataView the renal cancer PDO 2.0 studyStudy applications
Choose assays for the program objective
Explain response with more than one endpoint
Receive clear data, images and a study report
Study workflow
Connect model identity to multimodal assays
Select assays for the study objective
Start with the study priority—model identity, efficacy, mechanism or safety—then build the assay panel around it.
Model and batch QC
Use morphology, histology and cell-type markers to confirm the model is ready for the study.
Functional and molecular readouts
Combine viability, apoptosis, barrier, flow, qPCR or secreted readouts so complementary endpoints reinforce interpretation.
Analysis, interpretation and delivery
Bring raw data, analytical methods, QC and interpretation together in a traceable report.
Deliverables
Receive integrated data, images and analysis
- Model and batch QC
- Original images, flow or molecular data
- Analytical methods, statistics and study report
Related models
Select the model by biological context
Assay panels are built around a defined hypothesis, with controls, sample context, model QC and orthogonal confirmation supporting the mechanistic interpretation.
PROJECT DISCUSSION
Build the assay strategy for your study
Share your model, candidate and priority endpoints. We’ll recommend a focused assay panel, define QC and agree the deliverables up front.